intersectPSetWrapper: Wrapper to intersect PSets

Description Usage Arguments Value Author(s) See Also

View source: R/intersectPSetWrapper.R

Description

A wrapper to return the intersected PSets for cells and drugs attaining a minimum number of intersections.

Usage

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intersectPSetWrapper(
  datasets,
  minimum_intersection = 1,
  intersectOn = c("cell.lines", "drugs"),
  sensitivity_measure = "auc_recomputed",
  remove_noisy_curves = FALSE,
  remove_mislabelled_cells = FALSE,
  mislabelled_cells = NULL
)

Arguments

datasets

Vector of datasets to calculate intersections among

minimum_intersection

Number of experiments to calculate intersection across

intersectOn

Vetor of items to perform intersection across. Default is c'cell.lines','drugs')

sensitivity_measure

Vector of sensitivity measures to return

remove_noisy_curves

Remove noisy dose-response curves

remove_mislabelled_cells

Remove incorrectly-labelled cells

mislabelled_cells

Vector of cells to remove. If NULL, GDSC and CCLE mislabelled cells used.

Value

List of tibbles containing sensitivity information

Author(s)

Matthew Ploenzke, ploenzke@g.harvard.edu

See Also

formatSensitivities


mPloenzke/PharmacoMixtuR documentation built on Feb. 3, 2022, 12:13 p.m.