htn_outcome_classify: A Function to Classify continuous SBP and DBP outcomes as...

In margarethannum/PolygenicPTSD: Examine Interaction Between PTSD and Blood Pressure Polygenic Risk Score in Predicting Blood Pressure Outcomes

Description

This function allows you to create new categorical hypertension variables in your dataset based on old and new AHA guidelines.

Usage

htn_outcome_classify(data_entry)

Arguments

data_entry

Dataframe input that includes the variables SBP_meas, DBP_meas, and antihtn_use -0 or 1-

Details

OLD AHA BP CUTOFFS: Normotensive: SBP <120 mm Hg AND DBP <80 mm Hg Pre-hypertensive: SBP 120-139 mm Hg OR DBP 80-89 mm Hg Hypertensive: SBP <e2><89><a5>140 mm Hg OR DBP <e2><89><a5>90 mm Hg

NEW AHA BP CUTOFFS: Normotensive: SBP <120 mm Hg AND DBP <80 mm Hg Pre-hypertensive/Elevated: SBP 120-129 mm Hg AND DBP <80 mm Hg Hypertensive: SBP <e2><89><a5>130 mm Hg OR DBP <e2><89><a5>80 mm Hg

Value

Will return a new dataframe with 7 new variables:

htn_aha_old	Three categories (normotensive = 0, pre-hypertensive = 1, hypertensive = 2) of hypertension based on old AHA guidelines
htn_aha_new	Three categories (normotensive = 0, pre-hypertensive = 1, hypertensive = 2) of hypertension based on new AHA guidelines
htn_aha_old_bi	Two categories (non-hypertensive = 0, hypertensive = 1) of hypertension based on old AHA guidelines, grouping normo- and pre-hypertensive
htn_aha_new_bi	Two categories (non-hypertensive = 0, hypertensive = 1) of hypertension based on new AHA guidelines, grouping normo- and pre-hypertensive
SBP_meas_adj	New SBP outcome variable adjusting +10 for anti-hypertensive use
DBP_meas_adj	New DBP outcome variable adjusting +5 for anti-hypertensive use
ancestry	New binary variable for european (0) and african (1) ancestry (combines African and African American)

Examples

classed <- htn_outcome_classify(merged)

margarethannum/PolygenicPTSD documentation built on May 17, 2019, 8:16 p.m.