Description Classification functions Stratification functions Analysis functions
The polygenicPTSD package provides three categories of important functions: classification, stratification, and analysis.
The classification functions use imported continuous BP data and classifies categorical hypertension outcomes based on AHA guidelines (both old and new). ...
Stratifies data based on ancestry (European and African, based on availability of ancestry-specific PRS) and performs Fishers exact test to determine if dataset has significant difference between old and new AHA hypertension guidelines within ancestry.
Runs linear regression for continuous outcomes (SBP and DBP) and multinomial regression for categorical hypertension outcome, using base model which includes covariates for age, sex, and first three ancestry principle components, along with PTSD and PRS variables.
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