polygenicPTSD: polygenicPTSD: A package for examining interaction between...

Description Classification functions Stratification functions Analysis functions

Description

The polygenicPTSD package provides three categories of important functions: classification, stratification, and analysis.

Classification functions

The classification functions use imported continuous BP data and classifies categorical hypertension outcomes based on AHA guidelines (both old and new). ...

Stratification functions

Stratifies data based on ancestry (European and African, based on availability of ancestry-specific PRS) and performs Fishers exact test to determine if dataset has significant difference between old and new AHA hypertension guidelines within ancestry.

Analysis functions

Runs linear regression for continuous outcomes (SBP and DBP) and multinomial regression for categorical hypertension outcome, using base model which includes covariates for age, sex, and first three ancestry principle components, along with PTSD and PRS variables.


margarethannum/PolygenicPTSD documentation built on May 17, 2019, 8:16 p.m.