miaozhun/ImputeSingle: scRecover for imputation of single-cell RNA-seq data

scRecover is an R package for imputation of single-cell RNA-seq (scRNA-seq) data. It will detect and impute dropout values in a scRNA-seq raw read counts matrix while keeping the real zeros unchanged, since there are both dropout zeros and real zeros in scRNA-seq data. By combination with scImpute, SAVER and MAGIC, scRecover not only detects dropout and real zeros at higher accuracy, but also improve the downstream clustering and visualization results.

Getting started

Package details

AuthorZhun Miao, Xuegong Zhang <zhangxg@tsinghua.edu.cn>
Bioconductor views GeneExpression Preprocessing RNASeq Sequencing SingleCell Software Transcriptomics
MaintainerZhun Miao <miaoz13@tsinghua.org.cn>
LicenseGPL
Version1.15.1
URL https://miaozhun.github.io/scRecover
Package repositoryView on GitHub
Installation Install the latest version of this package by entering the following in R:
install.packages("remotes")
remotes::install_github("miaozhun/ImputeSingle")
miaozhun/ImputeSingle documentation built on Jan. 12, 2023, 8:06 p.m.