gsaPermute is an R package that can be used to create random gene sets of approximately the same composition (same number of genes with the same number of SNPs) as an a priori defined gene set (e.g. from a publicly available pathway database). As part of a gene set (pathway) analysis, this procedure can be used to calculate a null distribution of association statistics for each pathway being tested, which enables adjustment of p-values for pathway size and linkage disequilibrium (correlation between SNPs).
|Maintainer||Michael Mooney <[email protected]>|
|Package repository||View on GitHub|
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