mooneymi/gsaPermute: Gene Permutation Procedure for Unbiased Gene Set Analysis

gsaPermute is an R package that can be used to create random gene sets of approximately the same composition (same number of genes with the same number of SNPs) as an a priori defined gene set (e.g. from a publicly available pathway database). As part of a gene set (pathway) analysis, this procedure can be used to calculate a null distribution of association statistics for each pathway being tested, which enables adjustment of p-values for pathway size and linkage disequilibrium (correlation between SNPs).

Getting started

Package details

AuthorMichael Mooney
MaintainerMichael Mooney <[email protected]>
Package repositoryView on GitHub
Installation Install the latest version of this package by entering the following in R:
mooneymi/gsaPermute documentation built on May 22, 2017, 12:09 p.m.