In mvaniterson/wbccPredictor: A gene expression or DNA methylation based predictor for white blood cell counts

require(BiocStyle)
require(knitr)
markdown()
opts_chunk$set(eval=TRUE, tidy=TRUE, highlight=TRUE, fig.path="figures/")

!!! This is a project in development !!!

wbccPredictor

wbccPredictor can be used to build a predictor, using partial-least-squares, for WBCC based on gene expression or DNA methylation data. Or wbccPredictor can be used to predict WBCC using the build-in predictor for both gene expression and DNA methylation data.

Install

Installation requires the package devtools,

library(devtools)
install_github("mvaniterson/wbccPredictor")

or using the biocLite function downloaded from BioConductor.

source("http://bioconductor.org/biocLite.R")
biocLite("mvaniterson/wbccPredictor")

Using RNAseq data

Using DNA methylation data

see example R script for 450K data

TODO

• extend README
• remove imputation of NA's this should be up to the user

mvaniterson/wbccPredictor documentation built on May 23, 2019, 10:53 a.m.