Description Author(s) References See Also Examples
Power calculation for a joint analysis of a two-stage case control design for SNP data.
Anders Albrechtsen <albrecht@binf.ku.dk>
Skol AD, Scott LJ, Abecasis GR, Boehnke M: Joint analysis is more efficient than replication-based analysis for two-stage genome-wide association studies. Nat Genet 38: 209-213, 2006.
http://www.sph.umich.edu/csg/abecasis/CaTS/
1 2 3 4 5 6 7 8 | # calculate the power under a multiplicative model using a
# two stage design and assuming a relative risk of 1.5
cats(
freq = 0.2,
ncases = 500, ncases2 = 500,
ncontrols = 1000, ncontrols2 = 1000,
risk = 1.5, multiplicative = 1
)
|
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