cellularFraction: Cellular fraction

cellularFractionR Documentation

Cellular fraction

Description

Computes the maximum likelihood estimate of cancer cell fractions given observed VAF

Usage

alpha_hat = cellularFraction(f_hat, qt, sq)

Arguments

f_hat

numeric vector of variant allele fractions where f_hat = 0 1

qt

numeric vector of integer estimates of total copy numbers

sq

numeric vector of integer estimates of mutated copy numbers

Value

Numeric vector of cancer cell fractions where alpha_hat = 0 1

Author(s)


David Brown
brownd7@mskcc.org


ndbrown6/CNtu documentation built on March 16, 2023, 1:01 a.m.