neurogenomics/CHAS: Cell type deconvolution of bulk tissue histone acetylomes from epigenetic data

CHAS is an R package which integrates cell sorted H3K27ac data to identify cell type-specific peaks in bulk tissue H3K27ac profiles. Using the cell type-specific H3K27ac peaks, one can then calculate cell type-specific acetylation scores to act as a proxy for cell type proportion in the bulk tissue sample.

Getting started

Package details

Maintainer
LicenseGPL (>= 3) + file LICENSE
Version0.99.9
Package repositoryView on GitHub
Installation Install the latest version of this package by entering the following in R:
install.packages("remotes")
remotes::install_github("neurogenomics/CHAS")
neurogenomics/CHAS documentation built on Jan. 20, 2025, 4:03 p.m.