nhejazi/biotmle: Targeted Learning with Moderated Statistics for Biomarker Discovery
Version 1.5.1

This package facilitates the discovery of biomarkers from biological sequencing data (e.g., microarrays, RNA-seq) based on the associations of potential biomarkers with exposure and outcome variables by implementing an estimation procedure that combines a generalization of moderated statistics with targeted minimum loss-based estimates (TMLE) of parameters defined via causal inference (e.g., Average Treatment Effect) whose estimators admit asymptotically linear representations.

Getting started

Package details

AuthorNima Hejazi [aut, cre, cph], Alan Hubbard [aut, ths], Weixin Cai [ctb]
Bioconductor views DifferentialExpression GeneExpression Microarray RNASeq Sequencing
MaintainerNima Hejazi <[email protected]>
Licensefile LICENSE
URL https://github.com/nhejazi/biotmle
Package repositoryView on GitHub
Installation Install the latest version of this package by entering the following in R:
nhejazi/biotmle documentation built on Sept. 30, 2018, 7:52 a.m.