This package facilitates the discovery of biomarkers from biological sequencing data (e.g., microarrays, RNA-seq) based on the associations of potential biomarkers with exposure and outcome variables by implementing an estimation procedure that combines a generalization of moderated statistics with targeted minimum loss-based estimates (TMLE) of causal parameters (e.g., Average Treatment Effect) whose estimators admit asymptotically linear representations (in terms of influence functions).
|Author||Nima Hejazi [aut, cre, cph], Alan Hubbard [aut, ths], Weixin Cai [ctb]|
|Bioconductor views||DifferentialExpression GeneExpression ImmunoOncology Microarray RNASeq Sequencing|
|Maintainer||Nima Hejazi <[email protected]>|
|Package repository||View on GitHub|
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