do_ORA: Performs overexpression enrichment on logical protein vector...

View source: R/do_ORA.R

do_ORAR Documentation

Performs overexpression enrichment on logical protein vector with specified Ontology

Description

Performs overexpression enrichment on logical protein vector with specified Ontology

Usage

do_ORA(
  proteins,
  database,
  pvalueCutoff = 0.05,
  pAdjustMethod = "none",
  qvalueCutoff = 0.2,
  minGSSize = 10,
  maxGSSize = 500,
  algorithm = "classic",
  dataset
)

Arguments

proteins

character vector

database

database to use

pvalueCutoff

p-value/confidence threshold to exclude terms

pAdjustMethod

one of "none", "BH" (Benjamini-Hochberg correction), "hochberg", "bonferroni", "holm", "hommel", "BY", "fdr"

qvalueCutoff

q-value cutoff for annotations

minGSSize

minimum number of annotated proteins to be included

maxGSSize

maximum number of annotated proteins to be included

dataset

dataset


nicohuttmann/pOmics documentation built on Sept. 21, 2022, 9:28 a.m.