do_ORA_Reactome: Performs over-representation analysis using Reactome...

View source: R/do_ORA_Reactome.R

do_ORA_ReactomeR Documentation

Performs over-representation analysis using Reactome annotations

Description

Performs over-representation analysis using Reactome annotations

Usage

do_ORA_Reactome(
  proteins,
  pvalueCutoff = 0.05,
  pAdjustMethod = "none",
  qvalueCutoff = 0.2,
  minGSSize = 10,
  maxGSSize = 500,
  dataset,
  view = F,
  return.all = F,
  add.info = F
)

Arguments

proteins

numeric/logical vector of proteins indicating group

pvalueCutoff

p-value cutoff for annotations

pAdjustMethod

one of "none", "BH" (Benjamini-Hochberg correction), "hochberg", "bonferroni", "holm", "hommel", "BY", "fdr"

qvalueCutoff

q-value cutoff for annotations

minGSSize

minimum number of annotated proteins to be included

maxGSSize

maximum number of annotated proteins to be included

dataset

dataset

view

view results

return.all

return enrichResult object; useful for further analysis of enrichment results

add.info

add additional information to the results data frame


nicohuttmann/pOmics documentation built on Sept. 21, 2022, 9:28 a.m.