do_ORA_TERM2GENE: Performs over-representation analysis using Gene Ontology...

View source: R/do_ORA_TERM2GENE.R

do_ORA_TERM2GENER Documentation

Performs over-representation analysis using Gene Ontology annotations

Description

Performs over-representation analysis using Gene Ontology annotations

Usage

do_ORA_TERM2GENE(
  proteins,
  database,
  pvalueCutoff = 0.05,
  pAdjustMethod = "none",
  qvalueCutoff = 0.2,
  minGSSize = 3,
  maxGSSize = 500
)

Arguments

proteins

numeric/logical vector of proteins indicating group

database

TERM2GENE data frame

pvalueCutoff

p-value cutoff for annotations

pAdjustMethod

one of "none", "BH" (Benjamini-Hochberg correction), "hochberg", "bonferroni", "holm", "hommel", "BY", "fdr"

qvalueCutoff

q-value cutoff for annotations

minGSSize

minimum number of annotated proteins to be included

maxGSSize

maximum number of annotated proteins to be included


nicohuttmann/pOmics documentation built on Sept. 21, 2022, 9:28 a.m.