linear_model_ode: Generate linear pharmacokinetic model ordinary differential...

In nlmixrdevelopment/nlmixrExtra: Extension to nlmixr

Description

Generate linear pharmacokinetic model ordinary differential equation code

Usage

linear_model_ode(..., compartments = NULL)

linear_model_ode_threecmt_ev(ka, cl, q, q2, v, vp, vp2, compartments = NULL)

linear_model_ode_threecmt_iv(cl, q, q2, v, vp, vp2, compartments = NULL)

linear_model_ode_twocmt_ev(ka, cl, q, v, vp, compartments = NULL)

linear_model_ode_twocmt_iv(cl, q, v, vp, compartments = NULL)

linear_model_ode_onecmt_ev(ka, cl, v, compartments = NULL)

linear_model_ode_onecmt_iv(cl, v, compartments = NULL)

Arguments

...	passed to other methods
compartments	Character vector of compartment names
ka	Absorption rate as an unquoted string
cl	Clearanc as an unquoted string
q	Intercompartmental clearance between the first and second compartment as an unquoted string
q2	Intercompartmental clearance between the first and third compartment as an unquoted string
v	Central volume of distribution as an unquoted string
vp	First peripheral volume of distribution as an unquoted string
vp2	Second peripheral volume of distribution as an unquoted string

Value

A character vector of code to insert

Functions

• linear_model_ode_threecmt_ev: Three compartment extravascular model

• linear_model_ode_threecmt_iv: Three compartment intravascular model

• linear_model_ode_twocmt_ev: Two compartment extravascular model

• linear_model_ode_twocmt_iv: Two compartment extravascular model

• linear_model_ode_onecmt_ev: One compartment extravascular model

• linear_model_ode_onecmt_iv: One compartment intravascular model

Examples

# Manually specify the model to use
linear_model_ode_onecmt_ev(ka=ka_drug1, cl=cl_drug1, v=v_drug1)
# Automatically detect the model to use
linear_model_ode(ka=ka_drug1, cl=cl_drug1, v=v_drug1)

nlmixrdevelopment/nlmixrExtra documentation built on Dec. 22, 2021, 3:11 a.m.