example1: example1

Description Usage Format Details

Description

Very few responders

Usage

1

Format

A data frame with five variables: result, analyst, plate, subjectID, and treatment.

Details

40 biological samples (distinguished in variable subjectID) are analyzed at each of 3 days and on each of 3 plates per day variable treatment distinguishes negative controls ('negcontrol') from biological samples ('sample') there are 4 obs. of a negative control within each plate

normalize: log-transform and substract mean model structure: runs crossed with biological samples. when running a model with many parameters (random effects and residual variance different between subgroups), a simple model with 1 component is better than a 2-component mixture when running a mixture model with random effects and residual variance assumed equal in both subgroups, a 2-component mixture is better than a simple model with 1 component

irrespective of the model choice, the same 2 individuals are classified as responders in the 2-component mixture


nwstephens/RmixADAexamples documentation built on May 20, 2019, 2:40 p.m.