train_classification_celllines: Train KBMTL classifer on Breast Cancer celllines

Description Usage Arguments Value Author(s)

View source: R/train_classification_celllines.R

Description

Train KBMTL classifer on Breast Cancer celllines

Usage

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train_classification_celllines(combined_matrix, train_idx,
  cell_line_response = "cell_line_response_threshold_0.50_large_and_small_screen.RData",
  targetid = "target_id.txt", genelist = "Trusight_genes.csv")

Arguments

combined_matrix

(string): Tab separated table containing training and test data. Genes are in the rows and samples are in the columns.

train_idx

(numeric): Numeric comma separated list of index of the columns that contain the training data from the table in path_to_combined. Index 0 is the gene names. Ranges are colon spearated. eg. 1,2,4:10

cell_line_response

(string): cell_line_response_threshold_0.50_large_and_small_screen.RData. Cell line are rows and drugs are columns.

targetid

(string): path to target_id.txt. Converts to HUGO identifiers and filters to protein coding genes.

genelist

(string): path to gene list Trusight.csv. Used to filter genes associated with cancer. Make sure gene identifiers match.

Value

smmart_trained_machine_learning_model.RData

Author(s)

Janice Patterson


patterja/kbmtl documentation built on Oct. 6, 2020, 1:16 p.m.