preprocessFresco: Normalize data using flexible local regression using...

Description Usage Arguments

Description

Normalize data using flexible local regression using empirical controls

Usage

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preprocessFresco(object, useControls = TRUE, loessSpan = 0.1,
  fitLoess = TRUE, sdThreshold = 0.1, verbose = TRUE)

Arguments

object

MethylSet object

useControls

Should empirical controls be used to align and fit loess surfaces?

loessSpan

Supply span for fitting loess surface

fitLoess

Should loess curve be fitted after initial alignment and scaling?

sdThreshold

Threshold to filter empirical controls by standard deviation


paulmanser/fresco documentation built on May 24, 2019, 8:45 p.m.