calc_ck: Calculate Critval c Using Method 1

In paulowhite/DelayedGSD: Planning and analysis of group sequential trial with pipeline data

Calculate Critval c Using Method 1

Description

Calculate Critval c Using Method 1

calculate critval c based on the boundaries at interim.

Usage

calc_ck(
  uk,
  lk,
  Info.i,
  Info.d,
  Info.max = NULL,
  ImaxAnticipated = FALSE,
  rho_alpha = 2,
  alpha = 0.025,
  bindingFutility = TRUE
)

Arguments

uk	upper bounds for all analyses up to and including current stage k
lk	lower bounds for all analyses up to and including current stage k
Info.i	Information for all analyses up to and including current stage k
Info.d	Observed information at decision analysis k
Info.max	Maximum information
ImaxAnticipated	set to TRUE if c should be calculated according to Eq 15 in HJ because study was stopped early due to Imax reached
rho_alpha	value of rho used for type I error spending function
alpha	one-sided alpha level to be used for the study
bindingFutility	whether the futility stopping rule is binding

paulowhite/DelayedGSD documentation built on Nov. 1, 2023, 5:36 p.m.