run_structsearch: run_structsearch

In pharmpy/pharmr: Interface to the 'Pharmpy' 'Pharmacometrics' Library

run_structsearch

Description

Run the structsearch tool. For more details, see :ref:structsearch.

Usage

run_structsearch(
  model,
  results,
  type,
  search_space = NULL,
  b_init = NULL,
  emax_init = NULL,
  ec50_init = NULL,
  met_init = NULL,
  extra_model = NULL,
  strictness = "minimization_successful or (rounding_errors and sigdigs >= 0.1)",
  extra_model_results = NULL,
  dv_types = NULL,
  ...
)

Arguments

model	(Model) Pharmpy start model
results	(ModelfitResults) Results for the start model
type	(str) Type of model. Currently only 'drug_metabolite' and 'pkpd'
search_space	(str or ModelFeatures (optional)) Search space to test
b_init	(numeric (optional)) Initial estimate for the baseline for pkpd models.
emax_init	(numeric (optional)) Initial estimate for E_MAX (for pkpd models only).
ec50_init	(numeric (optional)) Initial estimate for EC_50 (for pkpd models only).
met_init	(numeric (optional)) Initial estimate for MET (for pkpd models only).
extra_model	(Model (optional)) Optional extra Pharmpy model to use in TMDD structsearch
strictness	(str (optional)) Results for the extra model
extra_model_results	(ModelfitResults (optional)) Strictness criteria
dv_types	(list(str=numeric) (optional)) Dictionary of DV types for TMDD models with multiple DV
...	Arguments to pass to tool

Value

(StructSearchResult) structsearch tool result object

Examples

## Not run: 
model <- load_example_model("pheno")
results <- load_example_modelfit_results("pheno")
run_structsearch(model=model, results=results, model_type='pkpd')

## End(Not run)

pharmpy/pharmr documentation built on Feb. 15, 2025, 3:22 a.m.