methotrexate: Methotrexate workers

In qingyuanzhao/CrossScreening: Cross-Screening in Observational Studies that Test Many Hypotheses

Description

Methotrexate is a drug used totreat cancer, but there is concern that it may itself be carcinogenic in healthy individuals who are exposed while either manufacturing or administering the drug. Deng et al. (2005) compared 21 workers engaged in the production of methotrexate to 21 unexp osed controls matched for age, gender, and smoking. The variables are (prefix "w" means exposed and "c" means control)

Mftcr

mutant frequency of TCR gene

Mfhrpt

mutant frequency of hprt gene

mtl

mean tail length

mtm

mean tail moment

id

identifier

sex

sex

age

age

smoke

smoking

years

exposure years

protection

protection measures, G for gloves, M for mask, N for none

mask

if the protection includes mask

Usage

data(methotrexate)

Format

A data.frame.

References

Deng, H., Zhang, M., He, J., Wu, W., Jin, L., Zheng, W., ... & Wang, B. (2005). Investigating genetic damage in workers occupationally exposed to methotrexate using three genetic end-points. Mutagenesis, 20(5), 351-357.

qingyuanzhao/CrossScreening documentation built on May 26, 2019, 11:35 a.m.