#' The CODEX index in COPD
#'
#' @param charlson_index The Charlson Index relates long-term mortality with the patient’s comorbidity. In general, no comorbidity is considered to be: 0-1 point, low comorbidity: 2 points, and high > 3 points.
#' @param fev A number for forced expiratory volume in one second (FEV1) expressed as percentage
#' @param mmrc A number for the dyspnea scale of modified Medical Research Council (mMRC)
#' @param exacerbation Severe exacerbations of COPD during the previous year (hospitalization or ED consultations).
#'
#' @return the CODEX index
#' @export
#'
#' @examples
#' almagro(charlson_index=1, fev=65, mmrc=1, exacerbation=2)
almagro <- function(charlson_index, fev, mmrc, exacerbation) {
if (charlson_index >= 0 & charlson_index <= 4) {
comorbidity <- 0
} else if (charlson_index >= 5 & charlson_index <= 7) {
comorbidity <- 1
} else {
comorbidity <- 2
}
if (fev >= 65) {
obstruction <- 0
} else if (fev >= 50 & fev <= 64) {
obstruction <- 1
} else if (fev >= 36 & fev <= 49) {
obstruction <- 2
} else {
obstruction <- 3
}
if (mmrc >= 0 & mmrc <= 1) {
dyspnea <- 0
} else if (mmrc == 2) {
dyspnea <- 1
} else if (mmrc == 3) {
dyspnea <- 2
} else {
dyspnea <- 3
}
if (exacerbation == 0) {
ex <- 0
} else if (exacerbation >= 1 & exacerbation <= 2) {
ex <- 1
} else {
ex <- 2
}
codex <- comorbidity + obstruction + dyspnea + ex
results <- list()
results$codex <- codex
return(results)
}
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