GetTD: Fit group regression for specific quantile and degree

In rhondabacher/SCnorm: Normalization of single cell RNA-seq data

Fit group regression for specific quantile and degree

Description

This is an internal fitting of the group regression. For a single combination of possible tau and d values the group regression is fist fit, then predicted values are obtained and regressed against the original sequencing depths. The estimates slope is passed back to the SCnorm_fit() function.

Usage

GetTD(x, InputData)

Arguments

x	specifies a column of the grid matrix of tau and d.
InputData	contains the expression values, sequencing depths to fit the group regression, and the quantile used in the individual gene regression for grouping.

Value

estimated count-depth relationship of predicted values for one value of tau and degree.

Author(s)

Rhonda Bacher

rhondabacher/SCnorm documentation built on July 8, 2023, 11:36 p.m.