sel.scores.inv.set: Creates an object indicating observations in core set

In rxmenezes/rscreenorm: Normalization of Multiple Genetic Screens Data

Description

This is an internal function that uses data_rscreen and a threshold object and returns a logical matrix, with the same dimensions as data_only, with TRUE for every lethality score in the core set, and FALSE for all others. To be used internally, it is called by get.inv.set.

Usage

sel.scores.inv.set(data_rscreen, th_obj)

Arguments

data_rscreen	an object of class 'rscreen.object', either yielded by read.screen.data, or by combine.screens. Typically the 'data_only' slot of this object contains lethality scores computed by get.leth.scores, which already reflect a value relative to negative and positive controls, per replicate.
th_obj	object containing thresholds per replicate, as returned by get.th.inv.set

Value

A logical matrix with the same number of columns as the data_only slot of data_rscreen, and as many rows as annotated with "sample" in the data_only slot

See Also

get.inv.set the wrapper that calls this functions and others to yield the resulting core sets, get.th.inv.set that produces the thresholds per replicate, get.rscreenorm to normalize data from multiple screens using core sets and get.leth.scores to compute scores that make observations in different screens comparable.

rxmenezes/rscreenorm documentation built on May 15, 2019, 1:19 p.m.