inst/ProstarApp/md/formerReleases.md

In samWieczorek/Prostar: Provides a GUI for DAPAR

News in Prostar 1.12

Bug fixed

• Normalization: "Sum by columns" has been modified to provide log-abundances compatible with subsequent processing.
• Normalization: Any normalization can now be applied "for each condition independantly" or "globally".
• Imputation: All methods are now only applied "for each condition independantly".

New features

• The entire pipeline is now compatible with datasets with more than 2 conditions.
• Descriptive statistics: The expression datasets are colored with respect to the nature of missing value (either POV or MEC, see below), even when the value has been imputed.
• Filtering: Manage designs with more than 2 conditions and with conditions containing different number of samples.
• Filtering: More user friendly interface for the string-based filtering (Tab 2).
• Imputation (protein level): Distinction between missing values on an entire condition (Missing on the Entire Condition - MEC) and the other ones (Partially Observed Value - POV).
• Imputation (protein level): for POV, it is possible to use SLSA which take into account the experimental design.
• Differential analysis: All tests can be applied on datasets with different number of samples in each condition.
• Differential analysis: Limma takes into account all the hierarchical experimental designs.
• GO analysis: the GeneID nomenclature is now available.

News in Prostar 1.10

Bug fixed

• not traced.

New features

• Gene Ontology (GO) analysis (Beta version).
• Automatic report generation (Beta).
• Preliminary separation between peptide and protein level pipelines.
• IMP4P method for peptide level imputation.
• DetQuantile method for protein level imputation.
• Tooltip implementation.

samWieczorek/Prostar documentation built on April 27, 2022, 7:32 a.m.