model | R Documentation |
This function creates the basis for a general pharmacometric model, a flexible but verbose model type.
model()
The function creates the foundation for a general pharmacometric model to which different building blocks can be added. The following building blocks are relevant for this model type:
Parameters: prm_log_normal, prm_logit_normal, prm_no_var, prm_normal
Observations: obs_additive, obs_combined, obs_proportional
Algebraic relationships: algebraic
Compartments: compartment
Flows: flow
Input variables: input_variable, dataset
The more specialized pk_model()
is converted to a general model during the rendering process.
A general pharmacometric model
m <- model() + input_variable("dose") + prm_log_normal("emax") + prm_log_normal("ed50") + obs_additive(eff~emax*dose/(ed50+dose)) render(m)
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