ConcTime: Example concentration-time data

In shirewoman2/LaurasHelpers: Miscellaneous Helper Functions for Common PK or Analytical Chemistry Tasks

Example concentration-time data

Description

Made up concentration-time data for a crossover study design in which subjects received drugs A and B both IV and subcutaneously. For convenience, fitted parameters and some metadata are included in the same data.frame, although I don't like how replicative this data.frame is.

Usage

ConcTime

Format

A data.frame with 1800 rows and 13 variables:

Drug

Drug administered

DoseRoute

Route of dose administation: IV or SC

SubjectID

Unique identifier for the subejct

k_meanpop

Mean estimate of the terminal elimination rate constant k for the population

Vd_meanpop

Mean estimate of the volume of distribution for the population

k

Estimate of the terminal elimination rate constant k for this subject

Vd

Estimate of the volume of distribution for this subject

Sex

Sex of the subject

Age

Subject's age

Occupation

Subject's occupation

TimeHr

Time (hr) since dose

Dose

Dose of the drug (mg)

Concentration

Plasma drug concentration (ng/mL)

shirewoman2/LaurasHelpers documentation built on Oct. 22, 2023, 2:07 p.m.