Description Usage Format Details Source
Associations between human body height and genetic markers. This is a random selection of 10'000 SNPs from summary statistics produced by the manuscript of Yengo et al. (2018).
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The data set contains 10 variables:
snp
SNP identifier
chr
Chromosome
pos
Physical position (Genome build hg19)
tested_allele
Allele corresponding to the effect size beta
other_allele
Other allele
freq_tested_allele_hrs
Frequency of the tested allele in the Health and Retirement Study (from 8,552 unrelated participants).
beta
(Marginal) effect size
se
Standard error of the effect size
p
P-value of the effect size
n
Sample size
The summary statistics by running a genome-wide association study (GWAS) for
height in ~700K individuals of European ancestry. Each line in the dataset corresponds
to the association between height (transformed) as an outcome and one genetic marker
(indicated in snp
) plus covariates as predictors.
Data: https://portals.broadinstitute.org/collaboration/giant/images/c/c8/Meta-analysis_Locke_et_al%2BUKBiobank_2018_UPDATED.txt.gz Data description: https://portals.broadinstitute.org/collaboration/giant/images/0/01/README_summary_statistics_Yengo_et_al_2018.txt Manuscript: Yengo et al. (2018) https://www.biorxiv.org/content/early/2018/03/22/274654
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