Description Usage Arguments Value References
View source: R/select-features.r
Gene selection based on the statistical significances according to the Snowball approach (see references for more details).
1 | select.features(x, cutoff.p = 0.05, p.adjust.method = "BH")
|
x |
an output from the main function
|
cutoff.p |
cutoff for top gene list. This is applied on the multiple testing adjusted p values |
p.adjust.method |
specifies a multiple testing
adjustment method, see |
a list with two elements - fullList
and
selectedList
.fullLIst
is a data.frame that
contains rd
, pval
and positive
,
corresponding respectively to the RD, p value and an
indicator variable of weather the RD value is above or
below the median value. selectedList
is a data.frame
that contains the same variables as those in
fullList
with only the top genes that satisfy the
significance cutoff specified by cutoff.p
.
Xu, Y., Guo, X., Sun, J. and Zhao. Z. Snowball: resampling combined with distance-based regression to discover transcriptional consequences of driver mutation, manuscript.
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