vl_msm: Viral Load Module

In statnet/PrEP-for-ASMM-and-adult-MSM: Network-Based Epidemic Modeling of HIV Transmission among MSM and ASMM populations

Description

Module function for updating HIV viral load.

Usage

vl_msm(dat, at)

Arguments

dat	Master data list object of class dat containing networks, individual-level attributes, and summary statistics.
at	Current time step.

Details

HIV viral load varies over time as a function of time since infection and ART history. In the absence of ART, VL rises during the acute rising stage and falls during the acute falling stage, until it reaches a set-point value in chronic stage infection. VL again rises during AIDS stage disease until the point of death.

For persons who have ever initated treatment (tt.traj is 3 or 4), VL changes depending on current ART use in that time step. Current use is associated with a reduction in VL, with the rates of decline and nadirs dependent on partial or full suppression levels. Current non-adherence is associated with an equal level of increase to VL. All persons who have reached AIDS, regardless of how they arrived, have a similar rate of VL increase.

Value

This function returns the dat object with updated vl attribute.

statnet/PrEP-for-ASMM-and-adult-MSM documentation built on June 22, 2019, 12:45 a.m.