README.md

In sueinchoi/KpCoeff: What the Package Does (One Line, Title Case)

KpCoeff

KpCoeff is an R package for prediction of tissue-plasma partition coefficients (Kp) using published method with published/unified dataset. KpCoeff is free and open-source software.

Resources

Unified dataset is from the reference

Reference

Installation

Install the current development version

library(devtools)
remotes::install_github("sueinchoi/KpCoeff")

Interaction

We welcome questions about anything KpCoeff: installation, dataset, how it works, reference, understanding better how KpCoeff works. We also welcome suggestions for how to make KpCoeff more useful to you and to the PBPK community.

Some examples

A simple simulation

library(KpCoeff)

Predict the tissue-plasma partition coefficient using P&T method with reference dataset

KpCoeff(1.9, 6.4, 0.01, 1, 3, "P&T", 0)

Predict the tissue-plasma partition coefficient using R&R method with unified dataset

KpCoeff(1.9, 6.4, 0.01, 1, 3, "R&R", 1)

The result can be direcly incorporated to the simulation model from mrgsolve package

Example of using KpCoeff result with mrgsolve package will be soon updated

sueinchoi/KpCoeff documentation built on Dec. 5, 2023, 5:29 a.m.