Kpcoeff_Berez: Prediction of tissue-prediction partition coefficient using...

In sueinchoi/KpCoeff: What the Package Does (One Line, Title Case)

Prediction of tissue-prediction partition coefficient using Berez method

Description

Prediction of tissue-prediction partition coefficient using Berez method

Usage

Kpcoeff_Berez(logP, pKa, fup, BP = 1, type = 1, dattype = 0)

Arguments

logP	Partition coefficient
pKa	Acid dissociation constant (for ampholyte or zwitterion, enter Acid pKa first)
fup	Plasma unbound fraction
BP	Blood-plasma ratio
type	Neutral(1)/acid(2)/base(3)/diprotic acid(4)/diprotic base(5)/zwitterion(ampholyte)(6)
dattype	Human physiology dataset(0 - original dataset, 1 - unified dataset)

Value

A list of tissue partition coefficient in each organ

Examples

Kpcoeff_Berez(2.7, 6, 0.9, 1, 1, 0)

sueinchoi/KpCoeff documentation built on Dec. 5, 2023, 5:29 a.m.