Amyloid: Amyloid-beta and Cognitive Impairment
In tessington/qsci381: Data used in QSCI 381, University of Washington
Description
Format
Details
Source
Description
Amyloid-beta and cognitive impairment for a sample of Catholic priests
Format
A data frame with 57 observations on the following 2 variables.
Group-
mAD=Alzheimer's, MCI=mild impairment, NCI=no impairment
AbetaAmount of Abeta from the posterior cingulate cortex (pmol/g tissue)
Details
Amyloid-beta (Abeta) is a protein fragment that has been linked to Alzheimer's disease. Autopsies from a sample of Catholic priests included measurements of Abeta (pmol/g tissue from the posterior cingulate cortex) from three groups: subjects who had exhibited no cognitive impairment before death, subjects who had exhibited mild cognitive impairment, and subjects who had mild to moderate Alzheimer's disease.
Source
Violetta N. Pivtoraiko, Eric E. Abrahamson, Sue E. Leurgans, Steven T. DeKosky,
Elliott J. Mufson,, Milos D. Ikonomovic (2015) Cortical pyroglutamate amyloid-beta levels and cognitive decline in Alzheimer's disease. Neurobiology of Aging (36) 12-19.
Data are read from Figure 1, panel d.
tessington/qsci381 documentation built on Sept. 26, 2020, 12:40 p.m.
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Description Format Details Source
Description
Amyloid-beta and cognitive impairment for a sample of Catholic priests
Format
A data frame with 57 observations on the following 2 variables.
Group-
mAD=Alzheimer's,MCI=mild impairment,NCI=no impairment AbetaAmount of Abeta from the posterior cingulate cortex (pmol/g tissue)
Details
Amyloid-beta (Abeta) is a protein fragment that has been linked to Alzheimer's disease. Autopsies from a sample of Catholic priests included measurements of Abeta (pmol/g tissue from the posterior cingulate cortex) from three groups: subjects who had exhibited no cognitive impairment before death, subjects who had exhibited mild cognitive impairment, and subjects who had mild to moderate Alzheimer's disease.
Source
Violetta N. Pivtoraiko, Eric E. Abrahamson, Sue E. Leurgans, Steven T. DeKosky, Elliott J. Mufson,, Milos D. Ikonomovic (2015) Cortical pyroglutamate amyloid-beta levels and cognitive decline in Alzheimer's disease. Neurobiology of Aging (36) 12-19. Data are read from Figure 1, panel d.
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