taNegbin.LimitRestMLE | R Documentation |
Limit of restricted maximum-likelihood estimator in case of negative binomial distributed endpoints
taNegbin.LimitRestMLE(
rateExp1,
rateRef1,
ratePla1,
shape1,
Delta,
allocation = c(1/3, 1/3, 1/3)
)
rateExp1 |
A numeric value specifying the rate of the experimental treatment group in the alternative hypothesis |
rateRef1 |
A numeric value specifying the rate of the reference treatment group in the alternative hypothesis |
ratePla1 |
A numeric value specifying the rate of the placebo treatment group in the alternative hypothesis |
shape1 |
A numeric value specifying the shape parameter |
Delta |
A numeric value specifying the non-inferiority/superiority margin |
allocation |
A (non-empty) vector specifying the sample size allocation (wExp, wRef, wPla) |
A list containing the following components:
rateExp0, rateRef0, rateRef0 |
The limit of the maximum-likelihood estimator for the rates when estimated restricted to the boundary of the null hypothesis |
shape0 |
The limit of the maximum-likelihood estimator for the shape parameter when estimated restricted to the boundary of the null hypothesis |
sigma2.rest |
The limit of the maximum-likelihood variance estimator for the Wald-type test when restricted to the boundary of the null hypothesis |
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