cancer: Microarray data set for breast cancer
In tuxette/internet3D: gamma-package for internet3D
Description
This gene expression data set is freely available, coming from
the Hess et al's paper. It concerns one hundred thirty-three patients
with stage I–III breast cancer. Patients were treated with chemotherapy
prior to surgery. Patient response to the treatment can be classified as
either a pathologic complete response (pCR) or residual disease (not-pCR).
Hess et al developed and tested a reliable multigene predictor for
treatment response on this data set, composed by a set of 26 genes having a
high predictive value.
Format
Two objects expr (a 26 by 133 matrix with expression levels)
and conditions a vector of conditions for the 26 patients.
References
K.R. Hess, K. Anderson, W.F. Symmans, V. Valero, N. Ibrahim, J.A.
Mejia, D. Booser, R.L. Theriault, U. Buzdar, P.J. Dempsey, R. Rouzier, N.
Sneige, J.S. Ross, T. Vidaurre, H.L. Gomez, G.N. Hortobagyi, and L. Pustzai
(2006) Pharmacogenomic predictor of sensitivity to preoperative chemotherapy
with Paclitaxel and Fluorouracil, Doxorubicin, and Cyclophosphamide in breast
cancer, Journal of Clinical Oncology, vol. 24(26), pp. 4236–4244.
tuxette/internet3D documentation built on May 8, 2019, 11:59 p.m.
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Description
This gene expression data set is freely available, coming from the Hess et al's paper. It concerns one hundred thirty-three patients with stage I–III breast cancer. Patients were treated with chemotherapy prior to surgery. Patient response to the treatment can be classified as either a pathologic complete response (pCR) or residual disease (not-pCR). Hess et al developed and tested a reliable multigene predictor for treatment response on this data set, composed by a set of 26 genes having a high predictive value.
Format
Two objects expr (a 26 by 133 matrix with expression levels)
and conditions a vector of conditions for the 26 patients.
References
K.R. Hess, K. Anderson, W.F. Symmans, V. Valero, N. Ibrahim, J.A. Mejia, D. Booser, R.L. Theriault, U. Buzdar, P.J. Dempsey, R. Rouzier, N. Sneige, J.S. Ross, T. Vidaurre, H.L. Gomez, G.N. Hortobagyi, and L. Pustzai (2006) Pharmacogenomic predictor of sensitivity to preoperative chemotherapy with Paclitaxel and Fluorouracil, Doxorubicin, and Cyclophosphamide in breast cancer, Journal of Clinical Oncology, vol. 24(26), pp. 4236–4244.
R Package Documentation
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We want your feedback!
Note that we can't provide technical support on individual packages. You should contact the package authors for that.
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