READ: Rectum adenocarcinoma

In waldronlab/curatedTCGAData: Curated Data from The Cancer Genome Atlas (TCGA) as MultiAssayExperiment Objects

Rectum adenocarcinoma

Description

A document describing the TCGA cancer code

Details

> experiments( READ )
ExperimentList class object of length 14: 
 [1] READ_CNASeq-20160128: RaggedExperiment with 56380 rows and 70 columns 
 [2] READ_CNASNP-20160128: RaggedExperiment with 156806 rows and 316 columns 
 [3] READ_CNVSNP-20160128: RaggedExperiment with 35765 rows and 316 columns 
 [4] READ_GISTIC_AllByGene-20160128: SummarizedExperiment with 24776 rows and 165 columns 
 [5] READ_GISTIC_Peaks-20160128: RangedSummarizedExperiment with 55 rows and 165 columns 
 [6] READ_GISTIC_ThresholdedByGene-20160128: SummarizedExperiment with 24776 rows and 165 columns 
 [7] READ_miRNASeqGene-20160128: SummarizedExperiment with 705 rows and 76 columns 
 [8] READ_mRNAArray-20160128: SummarizedExperiment with 17814 rows and 72 columns 
 [9] READ_Mutation-20160128: RaggedExperiment with 22075 rows and 69 columns 
 [10] READ_RNASeq2GeneNorm-20160128: SummarizedExperiment with 20501 rows and 72 columns 
 [11] READ_RNASeqGene-20160128: SummarizedExperiment with 20502 rows and 72 columns 
 [12] READ_RPPAArray-20160128: SummarizedExperiment with 208 rows and 131 columns 
 [13] READ_Methylation_methyl27-20160128: SummarizedExperiment with 27578 rows and 73 columns 
 [14] READ_Methylation_methyl450-20160128: SummarizedExperiment with 485577 rows and 106 columns 

> rownames( READ )
CharacterList of length 14
[["READ_CNASeq-20160128"]] character(0)
[["READ_CNASNP-20160128"]] character(0)
[["READ_CNVSNP-20160128"]] character(0)
[["READ_GISTIC_AllByGene-20160128"]] ACAP3 ... WASIR1|ENSG00000185203.7
[["READ_GISTIC_Peaks-20160128"]] chr1:3814904-31841618 ...
[["READ_GISTIC_ThresholdedByGene-20160128"]] ACAP3 ...
[["READ_miRNASeqGene-20160128"]] hsa-let-7a-1 hsa-let-7a-2 ... hsa-mir-99b
[["READ_mRNAArray-20160128"]] ELMO2 CREB3L1 RPS11 PNMA1 ... SNRPD2 AQP7 CTSC
[["READ_Mutation-20160128"]] character(0)
[["READ_RNASeq2GeneNorm-20160128"]] A1BG A1CF A2BP1 ... ZZZ3 psiTPTE22 tAKR
...
<4 more elements>

> colnames( READ )
CharacterList of length 14
[["READ_CNASeq-20160128"]] TCGA-AF-2691-01A-01D-1167-02 ...
[["READ_CNASNP-20160128"]] TCGA-AF-2687-01A-02D-1732-01 ...
[["READ_CNVSNP-20160128"]] TCGA-AF-2687-01A-02D-1732-01 ...
[["READ_GISTIC_AllByGene-20160128"]] TCGA-AF-2687-01A-02D-1732-01 ...
[["READ_GISTIC_Peaks-20160128"]] TCGA-AF-2687-01A-02D-1732-01 ...
[["READ_GISTIC_ThresholdedByGene-20160128"]] TCGA-AF-2687-01A-02D-1732-01 ...
[["READ_miRNASeqGene-20160128"]] TCGA-AF-2687-01A-02T-1735-13 ...
[["READ_mRNAArray-20160128"]] TCGA-AF-2689-11A-01R-1758-07 ...
[["READ_Mutation-20160128"]] TCGA-AF-2689-01A-01W-0831-10 ... TCGA-AG-A036-01
[["READ_RNASeq2GeneNorm-20160128"]] TCGA-AF-2691-01A-01R-0821-07 ...
...
<4 more elements>

Sizes of each ExperimentList element:

                                    assay size.Mb
1                    READ_CNASeq-20160128  1.5 Mb
2                    READ_CNASNP-20160128  4.3 Mb
3                    READ_CNVSNP-20160128  1.1 Mb
4          READ_GISTIC_AllByGene-20160128  4.9 Mb
5              READ_GISTIC_Peaks-20160128  0.1 Mb
6  READ_GISTIC_ThresholdedByGene-20160128  4.9 Mb
7              READ_miRNASeqGene-20160128  0.1 Mb
8                 READ_mRNAArray-20160128  1.1 Mb
9                  READ_Mutation-20160128  9.6 Mb
10          READ_RNASeq2GeneNorm-20160128  1.3 Mb
11               READ_RNASeqGene-20160128  1.3 Mb
12                READ_RPPAArray-20160128    0 Mb
13     READ_Methylation_methyl27-20160128  4.9 Mb
14    READ_Methylation_methyl450-20160128   75 Mb

---------------------------
Overall survival time-to-event summary (in years):
---------------------------

Call: survfit(formula = survival::Surv(colDat$days_to_death/365, colDat$vital_status) ~ 
    -1)

   142 observations deleted due to missingness 
      n  events  median 0.95LCL 0.95UCL 
  27.00   27.00    2.00    1.44    3.25 


---------------------------
Available sample meta-data:
---------------------------

years_to_birth:
   Min. 1st Qu.  Median    Mean 3rd Qu.    Max. 
  31.00   57.00   66.00   64.37   72.00   90.00 

vital_status:
  0   1 
141  28 

days_to_death:
   Min. 1st Qu.  Median    Mean 3rd Qu.    Max.    NA's 
   59.0   347.5   730.0   786.1  1193.0  1741.0     142 

days_to_last_followup:
   Min. 1st Qu.  Median    Mean 3rd Qu.    Max.    NA's 
    0.0   366.0   625.0   779.5  1096.0  3932.0      28 

tumor_tissue_site:
rectum   NA's 
   166      3 




pathology_M_stage:
  m0   m1  m1a   mx NA's 
 128   22    2   14    3 

gender:
female   male 
    77     92 

date_of_initial_pathologic_diagnosis:
   Min. 1st Qu.  Median    Mean 3rd Qu.    Max. 
   1999    2007    2009    2008    2010    2012 

days_to_last_known_alive:
   Min. 1st Qu.  Median    Mean 3rd Qu.    Max.    NA's 
   31.0   292.2   863.0  1420.1  2214.5  3667.0     161 

radiation_therapy:
  no  yes NA's 
 114   22   33 

histological_type:
         rectal adenocarcinoma rectal mucinous adenocarcinoma 
                           150                             13 
                          NA's 
                             6 

tumor_stage:
stage iia      NA's 
        1       168 

residual_tumor:
  r0   r1   r2   rx NA's 
 126    2   12    5   24 

number_of_lymph_nodes:
   Min. 1st Qu.  Median    Mean 3rd Qu.    Max.    NA's 
  0.000   0.000   0.000   2.692   3.000  31.000      10 

ethnicity:
    hispanic or latino not hispanic or latino                   NA's 
                     1                     84                     84 

Including an additional 2242 columns

See Also

READ-v2.0.1

waldronlab/curatedTCGAData documentation built on Nov. 14, 2024, 1:23 p.m.