qc_rlsc: QC based robust LOESS signal correction (QC-RLSC)

In wanchanglin/mtExtra: More functions for metabolomics data analysis

QC based robust LOESS signal correction (QC-RLSC)

Description

QC based robust LOESS (locally estimated scatterplot smoothing) signal correction (QC-RLSC)

Usage

qc_rlsc(x, y, method = c("subtract", "divide"), opti = TRUE, ...)

Arguments

x	A data frame with samples (row) and variables (column).
y	A vector with string of "qc" and "sample".
method	Data scaling method.
opti	A logical value indicating whether or not optimise 'span'
...	Other parameter for 'loess'.

Value

A corrected data frame.

References

Dunn et al. Procedures for large-scale metabolic profiling of serum and plasma using gas chromatography and liquid chromatography coupled to mass spectrometry. Nature Protocols 6, 1060–1083 (2011)

wanchanglin/mtExtra documentation built on Aug. 2, 2024, 5:47 p.m.