MIA_analysis: Title To integrate the scRNAseq and ST datasets, MIA method...

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MIA_analysisR Documentation

Title To integrate the scRNAseq and ST datasets, MIA method can analysis proceeds by first delineating sets of cell type-specific and tissue region-specific genes and then determining whether their overlap is higher (enrichment) or lower (depletion) than expected by chance.

Description

Title To integrate the scRNAseq and ST datasets, MIA method can analysis proceeds by first delineating sets of cell type-specific and tissue region-specific genes and then determining whether their overlap is higher (enrichment) or lower (depletion) than expected by chance.

Usage

MIA_analysis(sc_object, sp_object, sc_diff, sp_diff)

Arguments

sc_object

the seurat scRNA object

sp_object

the seurat scRNA object or spatial object

sc_diff

the different expression result of seurat analysis

sp_diff

the different expression result of seurat analysis

Value

data

Examples

# d = MIA_analysis(sc_object = stereo_smn, sp_object = stereo, sc_diff = sc_diff, sp_diff = sp_diff)

wangjiaxuan666/Spat documentation built on Jan. 4, 2023, 8:35 a.m.