predict.PCLasso: Make predictions from a PCLasso model

In weiliu123/PCLasso: A protein complex-based group lasso-Cox model for accurate prognosis and risk protein complex discovery

Description

Similar to other predict methods, this function returns predictions from a fitted PCLasso object.

Usage

## S3 method for class 'PCLasso'
predict(object, x = NULL, type = c("link", "response", "survival", 
"median", "norm", "coefficients", "vars", "nvars", "vars.unique", 
"nvars.unique", "groups", "ngroups"), lambda, ...)

Arguments

object	Fitted PCLasso model object.
x	Matrix of values at which predictions are to be made. The features (genes) contained in x should be consistent with those contained in x in the PCLasso function. Not used for type="coefficients" or for some of the type settings in predict.
type	Type of prediction: "link" returns the linear predictors; "response" gives the risk (i.e., exp(link)); "vars" returns the indices for the nonzero coefficients; "vars.unique" returns unique features (genes) with nonzero coefficients (If a feature belongs to multiple groups and multiple groups are selected, the feature will be repeatedly selected. Compared with "var", "var.unique" will filter out repeated features.); "groups" returns the groups with at least one nonzero coefficient; "nvars" returns the number of nonzero coefficients; "nvars.unique" returens the number of unique features (genes) with nonzero coefficients; "ngroups" returns the number of groups with at least one nonzero coefficient; "norm" returns the L2 norm of the coefficients in each group."survival" returns the estimated survival function; "median" estimates median survival times.
lambda	Values of the regularization parameter lambda at which predictions are requested. For values of lambda not in the sequence of fitted models, linear interpolation is used.
...	Arguments to be passed to predict.grpsurv in the R package grpreg.

Details

See predict.grpsurv in the R package grpreg for details.

Value

The object returned depends on type.

Author(s)

Wei Liu

See Also

PCLasso

Examples

library("survival")

# load data
data(ExpMatrix)
data(survData)
data(PCGroup)

set.seed(429006)
train.Idx <- sample(nrow(ExpMatrix), floor(2/3*nrow(ExpMatrix)))
x.train <- ExpMatrix[train.Idx ,]
x.test <- ExpMatrix[-train.Idx ,]
y.train <- survData[train.Idx,]
y.test <- survData[-train.Idx,]

fit1 <- PCLasso(x = x.train, 
                y = Surv(time=y.train[,"time"], event=y.train[,"status"]),
                group = PCGroup)

# predict risk scores of samples in x.test
s <- predict(object = fit1, x = x.test, type="link", lambda=fit1$fit$lambda)

s <- predict(object = fit1, x = x.test, type="link", lambda=fit1$fit$lambda[10])

s <- predict(object = fit1, x = x.test, type="link", lambda=c(0.1, 0.01))

# Nonzero coefficients
sel.groups <- predict(object = fit1, type="groups",
                      lambda = fit1$fit$lambda)
sel.ngroups <- predict(object = fit1, type="ngroups",
                       lambda = fit1$fit$lambda)
sel.vars.unique <- predict(object = fit1, type="vars.unique",
                           lambda = fit1$fit$lambda)
sel.nvars.unique <- predict(object = fit1, type="nvars.unique",
                            lambda = fit1$fit$lambda)
sel.vars <- predict(object = fit1, type="vars",
                    lambda=fit1$fit$lambda)
sel.nvars <- predict(object = fit1, type="nvars",
                     lambda=fit1$fit$lambda)


# For values of lambda not in the sequence of fitted models, 
# linear interpolation is used.
sel.groups <- predict(object = fit1, type="groups",
                      lambda = c(0.1, 0.01))
sel.ngroups <- predict(object = fit1, type="ngroups",
                       lambda = c(0.1, 0.01))
sel.vars.unique <- predict(object = fit1, type="vars.unique",
                           lambda = c(0.1, 0.01))
sel.nvars.unique <- predict(object = fit1, type="nvars.unique",
                            lambda = c(0.1, 0.01))
sel.vars <- predict(object = fit1, type="vars",
                    lambda=c(0.1, 0.01))
sel.nvars <- predict(object = fit1, type="nvars",
                     lambda=c(0.1, 0.01))

weiliu123/PCLasso documentation built on March 28, 2021, 3:51 a.m.