normMethod_rel_TIC: Normalize Relative Peak Intensity by Total Ion Current
In wesleyburr/subMaldi: Organization and Processing of MALDI-MS Datasets

Description Usage Arguments Value Note Author(s) References Examples

Called internally by normSpectra. Evaluates the sum of all intensities (TIC) of each spectrum in a dataset. If the TIC of all spectra are not equal, their intensities are multiplied by a normalization factor. Once the TIC of each spectrum has been standardized, the intensity of each peak in all spectra are divided by the normalized TIC. The resulting spectra will have individual TICs of 1. Capable of normalizing 1-6 spectra at once.

1	norm_rel_TIC(dat, mass_dat, spectra_cols)

`dat`	The name of the spectral data frame, containing `m/z` data in the first column and spectral intensity data in subsequent columns.
`mass_dat`	A character string; the name of the column in `dat` containing the m/z data for the spectrum.
`spectra_cols`	A character string; the names of the column in `dat` containing the intensity data for the spectrs to be analyzed.

Returns a new data frame including the original m/z data and normalized intensity data.

normSpectra

Kristen Yeh <kristenyeh@trentu.ca> Wesley Burr <wesleyburr@trentu.ca>

https://github.com/wesleyburr/subMaldi

## Load sample dataset "Master2.rda"
data("Master2")

# Normalize the TIC of "Before1" and "Before2"
ex <- normSpectra(dat = Master2, mass_dat = "full_mz", 
            method = "rel_TIC", spectra_cols = c("Before1", "Before2"))