CompareMCB | R Documentation |

This function is used to find the Methylation correlated blocks that differentially expressed between groups.
This function calculates attractors of all the MCBs among the groups and find the attractor MCBs.

CompareMCB( MCBs, method = c("attractors")[1], p_value = 0.05, min_CpGs = 5, platform = "Illumina Methylation 450K" )

`MCBs` |
Methylation correlated blocks list. |

`method` |
method used for calculation of differential expression, |

`p_value` |
p value threshold for the test. |

`min_CpGs` |
threshold for minimum CpGs must included in the individual MCBs. |

`platform` |
This parameter indicates the platform used to produce the methlyation profile. |

Currently, only illumina 450k platform is supported, the methylation profile need to convert into matrix format.

Object of class `list`

with elements:

`MCBsites` | Character set contains all CpG sites in MCBs. |

`MCBinformation` | Matrix contains the information of results. |

Xin Yu

Xin Yu, De-Xin Kong, EnMCB: an R/bioconductor package for predicting disease progression based on methylation correlated blocks using ensemble models, Bioinformatics, 2021, btab415

data('demo_data',package = "EnMCB")

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