Description Usage Arguments Details Value Examples
This function will detect signals for a given adverse drug event pair based on the biomedical literature (MEDLINE) using GEA.
1 | getPValue(drug, event, abstraction)
|
event |
The MeSH term for the adverse event of interest. |
abstraction |
The abstraction layer object for specified abstraction level. |
atccode |
The ATC code for the drug of interest. |
Calculates significane of co-occurrence of drug and adverse event in comparison to large reference set (all MEDLINE). Returns p-value for given drug - adverse event pair.
P-value for co-occurrence of a given drug - adverse event pair.
1 2 3 4 5 6 7 8 9 10 | {
library("GEA")
drugs <- Drugs("drugs_ATC_MEDLINE_360k.txt")
events <- AdverseEvents("manifestations_MEDLINE_360k.txt")
abs710 <- getAbstractionLayer(drugs,events,c(7,10))
getPValue("R03DC01","D058186",abs710)
}
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