clotu-package: Classification of OTUs

Description Details Author(s) References

Description

different OTU classification methods based on Gaussian assumption for non-zero OTUs

Details

Based on Kaul's assumption that non-zero OTUs follow a Gaussian distribution, this package incorporates the original model and its mutations with modifications in normalizing OTU counts, shrinking number of OTUs and 3 mutated models of calculating covariances.

Author(s)

Jun Li <yewei369@gmail.com>

References

A. Kaul, O. Davidov and S. D. Peddada, "Structural zeroes in high-dimensional data with applications to microbiome studies", Biostatistics, vol. 18, no. 3, p. 422-433, 2017.

Jun Li, "Classification of microbiome data with structural zeroes and small samples", master thesis at Link\"oping University, 2021


yewei369/clotu documentation built on Dec. 23, 2021, 7:19 p.m.