singleSNP: Simulating Single SNP Data

In ykim03517/reSNP: An efficient integrative resampling method for gene-trait association analysis

Description

Simulating Single SNP Data

Usage

singleSNP(size, geno_eff, grid = 0.01, c, MAF, pv = 0.5,
  cov_eff = 0.5)

Arguments

size	a numeric value of sample size.
geno_eff	a numeric value of genotype effect on phenotype.
grid	an interval of grid search (default=0.01; range: 0<grid<1). A lower value of grid gives denser intervals.
c	a numeric value of heterozygous genotype effect (0<=c<=1).
MAF	a numeric value of minor allele frequency (0<MAF<=0.5).
pv	a numeric value of prevalence of disease (default=0.5).
cov_eff	a numeric value of covariate effect on phenotype (default=0.5).

Value

a data set which consists of phenotype, genotype under additive assumption of genetic model, genotype under true genetic model, genotype matrix expanded with grid interval, and covariate.

Author(s)

Yeonil Kim

ykim03517/reSNP documentation built on Nov. 5, 2019, 1:20 p.m.