pkaeplot: Overlay adverse event duration on concentration-time curve...

In yoshidk6/PKAEvis: Visualize longitudinal adverse event data with pharmacokinetic profiles

Description

pkaeplot creates a plot showing duration of adverse events in each subjects overlayed on individual concentration-time curve

Usage

pkaeplot(pk, ae, subj, ae.data.first.day = 0, scale.y.log10 = T,
  x.range = NULL, y.range = NULL, ae.col.var = "AE", ae.col.name = NULL,
  pk.col.var = NULL, ae.palette = c("#56B4E9", "#0072B2", "#D55E00"),
  ggtheme = NULL)

Arguments

pk	dataset containing individual pharmacokinetic profiles
ae	dataset containing adverse event profiles
ae.data.first.day	assign 1 if the first study day is recorded as DAY=1 in AE dataset and DAY=0 in PK dataset
scale.y.log10	logical value controlling Y axis scale
x.range	range of X axis to display
y.range	range of Y axis to display for active arm
ae.col.var	variable to set colors of AE (e.g. AE grade, AE type)
ae.col.name	name appearing in legend for different colors of AE curves
pk.col.var	variable to set colors of background PK curves (e.g. DOSE)
ae.palette	color palette for AE scales
ggtheme	specify ggplot theme (set NULL to use current theme)

Details

The function returns a list of ggplot objects, including (1) plot for active arm, (2) plot for placebo arm, and (3) legend.

Value

list of ggplot objects

Examples

pkaeplot(pk = pk.sim.profile.sparse,
         ae = ae.sim.profile,
         ae.data.first.day = 1,
         y.range=c(0.3,3))

yoshidk6/PKAEvis documentation built on May 4, 2019, 5:33 p.m.