filterIsoDiffReport: Filter isoDiffReport

In yufree/x13cms: Untargeted isotope-based metabolomics

Filter isoDiffReport

Description

This routine filters an isoDiffReport to include only isotopologue groups that are differentially labeled between sample conditions and are not falsely unique due to suboptimal chromatography conditions. An additional, optional filter exists for the special case of 13C labeling experiments; it removes groups that consist only of M and M+1 peaks.

Usage

filterIsoDiffReport(isoDiffReport, alpha, whichPeak = 2)

Arguments

isoDiffReport	report to be filtered
alpha	p-value cutoff to call labeling pattern of isotoplogue group as different between sample conditions.
whichPeak	option for which isotopologue peaks within the group to consider when calling significance for differential labeling. Default = 1 indicates consideration of the relative intensities of the base peak only. '2' indicates consideration of all peaks and a call of significance if at least one of their relative intensities is significantly different between the two sample conditions.

Value

isoDiffReport

Author(s)

Xiaojing Huang

Examples

## Not run:
## filterIsoDiffReport(isoDiffReport, alpha = 0.05, whichPeak = 1, is13C = FALSE)   
 

yufree/x13cms documentation built on Feb. 7, 2024, 3:24 p.m.