In ywang297/CoxFlex: Flexible Modeling of the Time-to-Event Data

knitr::opts_chunk$set(
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This vignette documents the usage of the CoxFlex package, which implements a flexible extension of the Cox’s PH model allowing for non-linear (NL) and/or time-dependent (TD) effects of: 1) time-fixed; 2) time-varying covariates on the log hazard. The package also implements the backward elimination procedure to build flexible multivariable model for analyses that consider several, often inter-correlated, covariates with a priori unknown effects on the hazard.

The usage of the functions in the CoxFlex package is illustrated through analyzing the data from the survival package as examples. the use of the functions available in the FlexSurv package on an example with data available from the survival package. The current implementation of the FlexSurv package requires that the dataset is in an interval format. The FlexSurv package allows for fixed-in-time and time-dependent covariates. For additional statistical details on the selection and estimation of the flexible extension of the Cox’s model and its validation in simulations

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ywang297/CoxFlex documentation built on March 18, 2024, 3:26 a.m.