README.md

In zhanghfd/CCMO: Case-Control Mother-Offspring Pair Genetic Association Studies

CCMO

Installation of CCMO in R:

devtools::install_github('zhanghustc/CCMO')

Description of CCMO

This R package implements two novel statistical methods for detecting disease-associated SNPs using genotype data from case-control mother-offspring pairs, and each case or control has additional covariate data from his/her mother. The novel statistical methods are documented in the following manuscript:

1. Zhang H, Mukherjee B, Arthur V, Hu G, Hochner H, Chen J. An Efficient and Computationally Robust Statistical Method for Analyzing Case-Control Mother-Offspring Pair Genetic Association Studies. Annals of Applied Statistics, 2020, 14: 560–-584.

2. Zhang K, Zhang H, Chen J. Covariate Adjusted Inference of Parent-of-Origin Effects Using Case-Control Mother-Child Paired Multi-Locus Genotype Data. Manuscript.

zhanghfd/CCMO documentation built on March 18, 2021, 12:18 a.m.