eNull.TN: Maximum Likelihood Estimation of the Empirical Null

In zrmacc/LFDR: Local False Discovery Rate Estimation

Description

Estimates parameters of the empirical null distribution by fitting a truncated normal distribution within a "null neighborhood". Observations in the null neighborhood are assumed to arise from the null component of the mixture distribution.

Usage

eNull.TN(z, L, U, maxit = 10)

Arguments

z	Observations.
L	Lower limit of null neighborhood.
U	Upper limit of null neighborhood.
maxit	Maximum number of NR iterations.

Value

Estimated mean and variance of the null component, and the proportion of observations arising from the null component.

zrmacc/LFDR documentation built on May 3, 2019, 9:01 p.m.