PSM: Non-Linear Mixed-Effects modelling using Stochastic Differential Equations.

This package provides functions for estimation of linear and non-linear mixed-effects models using stochastic differential equations. Moreover it provides functions for finding smoothed estimates of model states and for simulation. The package allows for any multivariate non-linear time-variant model to be specified, and it also handels multidimentional input, co-variates, missing observations and specification of dosage regimen.

Author
Stig Bousgaard Mortensen <sbm@imm.dtu.dk> and Sren Klim <skl@imm.dtu.dk>
Date of publication
None
Maintainer
Authors <psmpackage@imm.dtu.dk>
License
GPL (>=2)
Version
0.8-5
URLs

View on R-Forge

Man pages

matexp
Matrix exponential
PSM.estimate
Estimate population parameters
PSM-internal
Internal functions in the PSM-package.
PSM-package
Population Stochastic Modelling
PSM.plot
Basic plots of data and output
PSM.simulate
Create simulation data for multiple individuals
PSM.smooth
Smoothing of model states based on estimated population...
PSM.template
Creates a template for a model in PSM

Files in this package

PSM
PSM/NAMESPACE
PSM/R
PSM/R/PSM.plot.R
PSM/R/invlogit.R
PSM/R/ExtKalmanSmoother.R
PSM/R/matexp.R
PSM/R/PSM.simulate.R
PSM/R/LinKalmanSmoother.R
PSM/R/IndividualLL.KF.gr.R
PSM/R/ExtKalmanFilter.R
PSM/R/LinKalmanFilter.R
PSM/R/IndividualLL.KF.R
PSM/R/CutThirdDim.R
PSM/R/zzz.R
PSM/R/logit.R
PSM/R/PSM.estimate.R
PSM/R/PSM.template.R
PSM/R/PSM.smooth.R
PSM/R/APL.KF.individualloop.R
PSM/R/APL.KF.R
PSM/R/APL.KF.gr.R
PSM/R/ModelCheck.R
PSM/inst
PSM/inst/doc
PSM/inst/doc/PSM.pdf
PSM/inst/doc/simisr.RData
PSM/inst/doc/simdose.RData
PSM/inst/doc/PSM.Rnw
PSM/inst/doc/images
PSM/inst/doc/images/comp2dose.eps
PSM/inst/doc/images/comp2dose.pdf
PSM/inst/doc/images/isrmodel.eps
PSM/inst/doc/images/isrmodel.pdf
PSM/DESCRIPTION
PSM/man
PSM/man/PSM.plot.Rd
PSM/man/PSM-package.Rd
PSM/man/PSM.estimate.Rd
PSM/man/PSM.simulate.Rd
PSM/man/PSM.template.Rd
PSM/man/matexp.Rd
PSM/man/PSM-internal.Rd
PSM/man/PSM.smooth.Rd
PSM/examples
PSM/examples/Heat_Data.csv
PSM/examples/Case_Heat.R
PSM/examples/example-dose-sim.R
PSM/examples/Scheme_2Comp.fig
PSM/examples/Simulation-TestCases.R
PSM/examples/PSMvsCTSM.Rnw
PSM/examples/Case_Bioreactor.RData
PSM/examples/TODO.txt
PSM/examples/example-supersimple.R
PSM/examples/examples.R
PSM/examples/Case_Bioreactor.R
PSM/examples/PSMvsCTSM.pdf
PSM/examples/BioReactorCTSMFilter.csv
PSM/examples/example-isr.R
PSM/examples/dosemodel.fig
PSM/examples/BioReactorCTSMSmooth.csv
PSM/examples/matexp_Examples.R
PSM/examples/CTSM_Heat_Xp.csv
PSM/examples/BioReactorCTSMPred.csv
PSM/examples/sde0_1.csv
PSM/examples/NL-deconv.R
PSM/src
PSM/src/LTI_KALMAN.f95
PSM/src/matexp.f
PSM/src/Makevars
PSM/src/matutil95.f95
PSM/src/matutil77.f