PSM: Non-Linear Mixed-Effects modelling using Stochastic Differential Equations.

This package provides functions for estimation of linear and non-linear mixed-effects models using stochastic differential equations. Moreover it provides functions for finding smoothed estimates of model states and for simulation. The package allows for any multivariate non-linear time-variant model to be specified, and it also handels multidimentional input, co-variates, missing observations and specification of dosage regimen.

AuthorStig Bousgaard Mortensen <sbm@imm.dtu.dk> and Sren Klim <skl@imm.dtu.dk>
Date of publicationNone
MaintainerAuthors <psmpackage@imm.dtu.dk>
LicenseGPL (>=2)
Version0.8-5
http://www.imm.dtu.dk/psm

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Files

NAMESPACE
R
R/PSM.plot.R R/invlogit.R R/ExtKalmanSmoother.R R/matexp.R R/PSM.simulate.R R/LinKalmanSmoother.R R/IndividualLL.KF.gr.R R/ExtKalmanFilter.R R/LinKalmanFilter.R R/IndividualLL.KF.R R/CutThirdDim.R R/zzz.R R/logit.R R/PSM.estimate.R R/PSM.template.R R/PSM.smooth.R R/APL.KF.individualloop.R R/APL.KF.R R/APL.KF.gr.R R/ModelCheck.R
inst
inst/doc
inst/doc/PSM.pdf
inst/doc/simisr.RData
inst/doc/simdose.RData
inst/doc/PSM.Rnw
inst/doc/images
inst/doc/images/comp2dose.eps
inst/doc/images/comp2dose.pdf
inst/doc/images/isrmodel.eps
inst/doc/images/isrmodel.pdf
DESCRIPTION
man
man/PSM.plot.Rd man/PSM-package.Rd man/PSM.estimate.Rd man/PSM.simulate.Rd man/PSM.template.Rd man/matexp.Rd man/PSM-internal.Rd man/PSM.smooth.Rd
examples
examples/Heat_Data.csv
examples/Case_Heat.R examples/example-dose-sim.R
examples/Scheme_2Comp.fig
examples/Simulation-TestCases.R
examples/PSMvsCTSM.Rnw
examples/Case_Bioreactor.RData
examples/TODO.txt
examples/example-supersimple.R examples/examples.R examples/Case_Bioreactor.R
examples/PSMvsCTSM.pdf
examples/BioReactorCTSMFilter.csv
examples/example-isr.R
examples/dosemodel.fig
examples/BioReactorCTSMSmooth.csv
examples/matexp_Examples.R
examples/CTSM_Heat_Xp.csv
examples/BioReactorCTSMPred.csv
examples/sde0_1.csv
examples/NL-deconv.R
src
src/LTI_KALMAN.f95
src/matexp.f
src/Makevars
src/matutil95.f95
src/matutil77.f

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