This package allows one to randomize subjects based on prognostic factors using the Pocock Simon (1975) minimization method
|License:||GPL (version 2 or later)|
The package is used as follows. First create a
object using the function
ClinicalExperiment class and then a
randomizer using a
PocockSimonRandomizer class. The function
randomize will randomize subjects to treatments. Read the
vignette for a complete example.
Maintainer: Balasubramanian Narasimhan<[email protected]>
Sequential Treatment Assigment with Balancing for Prognostic Factors in the Controlled Clinical Trial, by S.~J.~Pocock and R.~Simon, Biometrics, 31, 103-115
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## ## Please refer to the vignette ##
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