PRS-package: Randomized patients based on Pocock-Simon minimization method

Description Details Author(s) References Examples


This package allows one to randomize subjects based on prognostic factors using the Pocock Simon (1975) minimization method


Package: PRS
Type: Package
Version: 0.01
Date: 2007-08-20
License: GPL (version 2 or later)

The package is used as follows. First create a ClinicalExperiment object using the function ClinicalExperiment class and then a randomizer using a PocockSimonRandomizer class. The function randomize will randomize subjects to treatments. Read the vignette for a complete example.


Balasubramanian Narasimhan

Maintainer: Balasubramanian Narasimhan<>


Sequential Treatment Assigment with Balancing for Prognostic Factors in the Controlled Clinical Trial, by S.~J.~Pocock and R.~Simon, Biometrics, 31, 103-115


## Please refer to the vignette

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